DE3485693D1 - Menschlicher, insulinaehnlicher wachstumsfaktor (igf)hergestellt aus einem rekombinanten wirt, verfahren, expressionsvektor und rekombinanter wirt hierfuer und igf enthaltende pharmazeutische zusammensetzung. - Google Patents

Menschlicher, insulinaehnlicher wachstumsfaktor (igf)hergestellt aus einem rekombinanten wirt, verfahren, expressionsvektor und rekombinanter wirt hierfuer und igf enthaltende pharmazeutische zusammensetzung.

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Publication number
DE3485693D1
DE3485693D1 DE8484303783T DE3485693T DE3485693D1 DE 3485693 D1 DE3485693 D1 DE 3485693D1 DE 8484303783 T DE8484303783 T DE 8484303783T DE 3485693 T DE3485693 T DE 3485693T DE 3485693 D1 DE3485693 D1 DE 3485693D1
Authority
DE
Germany
Prior art keywords
igf
recombinant host
insulin
human
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE8484303783T
Other languages
English (en)
Inventor
James Mon Lee
Axel Ullrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
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Genentech Inc
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Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27053789&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3485693(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DE3485693D1 publication Critical patent/DE3485693D1/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/485Epidermal growth factor [EGF] (urogastrone)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/65Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
DE8484303783T 1983-06-06 1984-06-05 Menschlicher, insulinaehnlicher wachstumsfaktor (igf)hergestellt aus einem rekombinanten wirt, verfahren, expressionsvektor und rekombinanter wirt hierfuer und igf enthaltende pharmazeutische zusammensetzung. Revoked DE3485693D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50135383A 1983-06-06 1983-06-06
US50607883A 1983-06-20 1983-06-20

Publications (1)

Publication Number Publication Date
DE3485693D1 true DE3485693D1 (de) 1992-06-11

Family

ID=27053789

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484303783T Revoked DE3485693D1 (de) 1983-06-06 1984-06-05 Menschlicher, insulinaehnlicher wachstumsfaktor (igf)hergestellt aus einem rekombinanten wirt, verfahren, expressionsvektor und rekombinanter wirt hierfuer und igf enthaltende pharmazeutische zusammensetzung.

Country Status (10)

Country Link
US (3) US6331414B1 (de)
EP (1) EP0128733B1 (de)
JP (2) JP2608870B2 (de)
KR (1) KR850000525A (de)
AU (1) AU594301B2 (de)
DE (1) DE3485693D1 (de)
DK (1) DK172480B1 (de)
ES (1) ES8603955A1 (de)
IE (1) IE58317B1 (de)
IL (1) IL71991A (de)

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USRE39355E1 (en) 2006-10-17
ES8603955A1 (es) 1986-01-16
IL71991A0 (en) 1984-10-31
JPS6069029A (ja) 1985-04-19
DK276184A (da) 1985-01-21
US6331609B1 (en) 2001-12-18
JPH0759578A (ja) 1995-03-07
AU2913384A (en) 1984-12-13
KR850000525A (ko) 1985-02-27
IL71991A (en) 1994-05-30
EP0128733B1 (de) 1992-05-06
US6331414B1 (en) 2001-12-18
DK276184D0 (da) 1984-06-04
EP0128733A1 (de) 1984-12-19
DK172480B1 (da) 1998-10-05
ES533170A0 (es) 1986-01-16
AU594301B2 (en) 1990-03-08
JP2608870B2 (ja) 1997-05-14
IE841400L (en) 1984-12-06
IE58317B1 (en) 1993-09-08

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